DeSimone Orthodontics

Combining Artistry and Advanced Technology to Create Exceptional SmilesDr. DeSimone Orthodontics

Orthodontic problems require specialized care. Patients who have dental and facial irregularities should see an orthodontist. As a Board-Certified  Orthodontist Dr. Karen E. DeSimone has the  specific qualifications in the design, application and control of braces, retainers, and removable appliances to bring teeth, lips and jaws into proper alignment for optimal facial balance. The practice of Dr. DeSimone has state-of-the-art equipment and experience to provide the finest quality orthodontic treatment and to address today’s most demanding orthodontic needs in a friendly and caring environment. Office FrontWe are located at:

2 Tree Farm Road, Suite B-200,
Pennington, NJ
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Please call us at Karen DeSimone, DDS Orthodontist Phone Number 609-737-8000 or email us at [email protected] and we will be happy to schedule a complimentary consultation for you. We invite you to fill out our secure online patient information forms prior to your visit. Our goal is to provide you with the highest standard of orthodontic treatment and an enjoyable experience. We are happy that you are visiting our web site. Please feel free to e-mail or call us with any questions. Thank you for stopping by!

DeSimone Orthodontics

5 out of 5 stars based on 307 reviews.

Patient Testimonial from Christine P

We love Dr. DeSimone and the staff. Both my sons had braces and I also was a patient who went through Invisalign. I couldn’t be happier all around.

- Christine P

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Patient Testimonial from Kim W

My girls have seen Dr. DeSimone for several years for orthodontics. The office staff and environment is very warm and welcoming. They are very good at helping kids adjust to being in the office as well as having orthodontic appliances in their mouth, even for sensitive children. We’ve been very pleased with the results as well. I highly recommend Dr. DeSimone!

- Kim W

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Patient Testimonial from Penny X

We are very happy with Dr. DeSimone and staff. The end result is amazing and they are so easy to work with.

- Penny X

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Patient Testimonial from Sonal A

Awesome experience.Very less time consuming.

- Sonal A

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Patient Testimonial from Em Y

So incredibly happy with everything !! Highly recommended !

- Em Y

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Patient Testimonial from Charles P

Dr. DeSimone was wonderful for both of our children. Highly recommend her.

- Charles P

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Patient Testimonial from Cathy R

We had a wonderful experience at DeSimone Orthodontics. The staff is friendly, helpful and professional. Dr. DeSimone is amazing, and we highly recommend her office!

- Cathy R

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Patient Testimonial from Kevin P

I have two kids coming to DeSimone orthodontics and they are having amazing results with their overall procedures.

- Kevin P

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Patient Testimonial from Laurie B

DeSimone is a perfectionist, with a sweet nature. She got the realignment perfect.

- Laurie B

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Patient Testimonial from Aymara C

We love coming here! Staff is so kind and courteous and they make it fun for the kids. Staff provides guidance on the child’s needs and progress and provides financial options. Will definitely recommend this doctor to friends!

- Aymara C

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Patient Testimonial from Tayra B

Couldn’t be happier with our experiences here. Their mouths look great and the staff are friendly and professional.

- Tayra B

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Patient Testimonial from Marilyn S

It has been over 3 years since my son's treatment is complete and we get compliments on his beautiful teeth all the time! Dentists even ask where he has had his work done. We love DeSimone Orthodontics and highly recommend you visit when in need of Orthodontics! The staff even remember my daughter who was a toddler when our son was getting treatment! It's her turn now and we are so happy to be back.

- Marilyn S

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Patient Testimonial from Jennifer G

Getting Invisalign from Dr. DeSimone was so easy! The staff is courteous, friendly, and professional. My visits have been quick and efficient. Wearing Invisalign has been trouble-free, and I am able to see results weekly. I only wish that I had done this sooner with Dr. DeSimone!

- Jennifer G

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Patient Testimonial from Michele T

Very friendly and helpful office staff! Dr. DeSimone is informative, caring and supportive. Would highly recommend!!

- Michele T

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Patient Testimonial from Debbie K

Been a great experience! Very pleased!

- Debbie K

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Patient Testimonial from Janice M

Very professional and friendly staff treating each patient with individualized care for their personal orthodontic needs. I highly recommend Dr DeSimone and her team.

- Janice M

5 out of 5 stars on

Patient Testimonial from Brittany V

I have personally been treated by Dr. Desimone as well as my daughter! We can’t say enough good things about our experience! Dr. Desimone is so knowledgeable and only recommends what she believes is the best treatment! The staff is so outstanding and friendly as well and only provide quality care for their patients! Thank you Desimone Team!

- Brittany V

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Patient Testimonial from Rachel S

The staff was wonderful and so friendly. I have recommended Dr. DeSimone to several people. We have all been happy with the service and results.

- Rachel S

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Patient Testimonial from Amy D

We have had a great experience both with Dr. DeSimone and the office staff. All appointments have started on time and have been very efficient.

- Amy D

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Patient Testimonial from Carolyn S

We love Dr. DeSimone. She's brilliant. Everyone on her staff has been wonderful.

- Carolyn S

5 out of 5 stars on

American Board of Orthodontics Diplomate logo

DeSimone Orthodontics provides exceptional care with…

  • Increased comfort & decreased treatment time utilizing state-of-the-art techniques.
  • Artistry to maintain & improve facial esthetics.
  • OrthoCad Computer Imaging to illustrate virtual smile design prior to treatment.
  • Advanced technology including digital radiology reducing x-ray exposure by 90%.
  • Premier Provider Level of Invisalign.
  • Highly trained and compassionate staff.
  • The most translucent clear braces.
  • Accessibility for after-hours emergencies.
  • On-time appointments.
  • Variety of payment options including interest – free financing.
  • Help to maximize insurance coverage.
  • Monthly contests and patient appreciation events (ask us about DeSimone Dollars).
  • Annual Patient and Family Party.
  • Video arcade and coffee bar.
  • Visit our Pinterest Page!
 Patient using touch screen
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 Smiling patient